![]() ![]() They demonstrated diurnal baseline IOP of 24.1 ± 2.4 mmHg. Results: Thirty-two patients completed this study. Patients were then switched to the opposite treatment and underwent a second diurnal evaluation at the end of Period 2. Methods: Following a 6-week, medicine-free period, qualified patients were randomized for Period 1 to either placebo administered every morning and latanoprost every evening or to PTFC administered twice daily. Purpose: This study aimed to compare the safety and effect on intraocular pressure (IOP) of latanoprost given every evening versus pilocarpine/timolol maleate fixed combination (PTFC) given twice daily in patients with primary open-angle glaucoma (POAG) or ocular hypertension (OH). ![]()
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